3-Hydroxypropionaldehyde

• CAT Number: M015349
• CAS Number: 2134-29-4
• Molecular Formula: C3H6O2
• Molecular Weight: 74.079
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 3-hydroxypropanal
• InChI: InChI=1S/C3H6O2/c4-2-1-3-5/h2,5H,1,3H2
• InChIKey: AKXKFZDCRYJKTF-UHFFFAOYSA-N
• SMILES: C(CO)C=O

3-Hydroxypropionaldehyde (Cat.No:M015349) is a chemical compound used in various industrial applications. It’s a key intermediate in the production of acrylic acid, glycerol, and other chemicals. It can be derived from glycerol or glycerol-containing waste streams and has potential in biorefinery processes for sustainable chemical synthesis and value-added products.

Reference

1: Zaushitsyna O, Dishisha T, Hatti-Kaul R, Mattiasson B. Crosslinked,
cryostructured Lactobacillus reuteri monoliths for production of
3-hydroxypropionaldehyde, 3-hydroxypropionic acid and 1,3-propanediol from
glycerol. J Biotechnol. 2017 Jan 10;241:22-32. doi:
10.1016/j.jbiotec.2016.11.005. Epub 2016 Nov 6. PubMed PMID: 27829124.

2: Maervoet VE, De Maeseneire SL, Avci FG, Beauprez J, Soetaert WK, De Mey M.
High yield 1,3-propanediol production by rational engineering of the
3-hydroxypropionaldehyde bottleneck in Citrobacter werkmanii. Microb Cell Fact.
2016 Jan 28;15:23. doi: 10.1186/s12934-016-0421-y. PubMed PMID: 26822953; PubMed
Central PMCID: PMC4731958.

3: Sabet-Azad R, Sardari RR, Linares-Pastén JA, Hatti-Kaul R. Production of
3-hydroxypropionic acid from 3-hydroxypropionaldehyde by recombinant Escherichia
coli co-expressing Lactobacillus reuteri propanediol utilization enzymes.
Bioresour Technol. 2015 Mar;180:214-21. doi: 10.1016/j.biortech.2014.12.109. Epub
2015 Jan 7. PubMed PMID: 25614245.

4: Sardari RR, Dishisha T, Pyo SH, Hatti-Kaul R. Semicarbazide-functionalized
resin as a new scavenger for in situ recovery of 3-hydroxypropionaldehyde during
biotransformation of glycerol by Lactobacillus reuteri. J Biotechnol. 2014 Dec
20;192 Pt A:223-30. PubMed PMID: 25456063.

5: Su M, Li Y, Ge X, Tian P. 3-Hydroxypropionaldehyde-specific aldehyde
dehydrogenase from Bacillus subtilis catalyzes 3-hydroxypropionic acid production
in Klebsiella pneumoniae. Biotechnol Lett. 2015 Mar;37(3):717-24. doi:
10.1007/s10529-014-1730-z. Epub 2014 Nov 20. PubMed PMID: 25409630.

6: Dishisha T, Pereyra LP, Pyo SH, Britton RA, Hatti-Kaul R. Flux analysis of the
Lactobacillus reuteri propanediol-utilization pathway for production of
3-hydroxypropionaldehyde, 3-hydroxypropionic acid and 1,3-propanediol from
glycerol. Microb Cell Fact. 2014 May 27;13:76. doi: 10.1186/1475-2859-13-76.
PubMed PMID: 24886501; PubMed Central PMCID: PMC4045878.

7: Tajima T, Fuki K, Kataoka N, Kudou D, Nakashimada Y, Kato J. Construction of a
simple biocatalyst using psychrophilic bacterial cells and its application for
efficient 3-hydroxypropionaldehyde production from glycerol. AMB Express. 2013
Dec 5;3(1):69. doi: 10.1186/2191-0855-3-69. PubMed PMID: 24314120; PubMed Central
PMCID: PMC4029479.