For research use only. Not for therapeutic Use.
Zuclomiphene Citrate(CAT: R045289) is the cis-isomer of clomiphene citrate, a selective estrogen receptor modulator (SERM). Unlike its trans-isomer, enclomiphene, which has stronger anti-estrogenic effects, Zuclomiphene exhibits partial estrogen agonist activity. It binds to estrogen receptors in the hypothalamus and pituitary, influencing gonadotropin release and reproductive hormone regulation. Clinically, clomiphene mixtures have been used for female infertility treatment and are under investigation for male hypogonadism. Zuclomiphene’s estrogenic profile makes it particularly relevant for studies on menopause, hormone replacement, and metabolic regulation. As a stereochemically defined compound, it is a valuable tool for endocrinology and reproductive health research.
CAS Number | 7619-53-6 |
Synonyms | 2-[4-[(Z)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid |
Molecular Formula | C32H36ClNO8 |
Purity | ≥95% |
IUPAC Name | 2-[4-[(Z)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid |
InChI | InChI=1S/C26H28ClNO.C6H8O7/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,3-4,19-20H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-; |
InChIKey | PYTMYKVIJXPNBD-OQKDUQJOSA-N |
SMILES | CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
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