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Z-LEU-VAL-GLY-DIAZOMETHYLKETONE

Z-LEU-VAL-GLY-DIAZOMETHYLKETONE

  • CAT Number: M016383
  • CAS Number: 119670-30-3
  • Molecular Formula: C22H31N5O5
  • Molecular Weight: 445.52
  • Purity: ≥95%
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Z-LEU-VAL-GLY-DIAZOMETHYLKETONE (Cat.No:M016383) is a chemical compound used as a specific inhibitor of serine proteases, particularly granzyme B, an enzyme involved in immune responses and cell apoptosis. By irreversibly binding to the active site of granzyme B, it blocks its activity, making it a valuable tool in immunological research and potential therapeutic applications.

Catalog Number M016383
CAS Number 119670-30-3
Molecular Formula

C22H31N5O5

Purity 95%
Storage Desiccate at -20C
IUPAC Name (Z)-1-diazonio-3-[[3-methyl-2-[[4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]butanoyl]amino]prop-1-en-2-olate
InChI InChI=1S/C22H31N5O5/c1-14(2)10-18(26-22(31)32-13-16-8-6-5-7-9-16)20(29)27-19(15(3)4)21(30)24-11-17(28)12-25-23/h5-9,12,14-15,18-19H,10-11,13H2,1-4H3,(H3-,24,26,27,28,29,30,31)/b17-12-
InChIKey QDGQDRILMOHMTP-ATVHPVEESA-N
SMILES CC(C)CC(C(=O)NC(C(C)C)C(=O)NCC(=C[N+]#N)[O-])NC(=O)OCC1=CC=CC=C1

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