XL-147

  • CAT Number: I005671
  • CAS Number: 956958-53-5
  • Molecular Formula: C₂₁H₁₆N₆O₂S₂
  • Molecular Weight: 448.52
  • Purity: ≥95%
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XL-147 (Cat.No:I005671) is a promising chemical compound with significant implications in oncology research. As a selective inhibitor of the PI3K enzyme, XL-147 shows potential in targeting cancer cells and halting their growth. Preclinical studies have demonstrated encouraging results, making XL-147 a compelling candidate for future cancer therapies.

Catalog Number I005671
CAS Number 956958-53-5
Molecular Formula

C₂₁H₁₆N₆O₂S₂

Purity 95%
Target PI3K
Solubility DMSO ≥86mg/mL Water <1.2mg/mL Ethanol <1.2mg/mL
Storage 3 years -20℃ powder
IUPAC Name N-[3-(2,1,3-benzothiadiazol-5-ylamino)quinoxalin-2-yl]-4-methylbenzenesulfonamide
InChI InChI=1S/C25H25ClN6O4S/c1-25(2,27)24(33)28-15-7-6-8-17(13-15)37(34,35)32-23-22(29-19-9-4-5-10-20(19)30-23)31-21-14-16(36-3)11-12-18(21)26/h4-14H,27H2,1-3H3,(H,28,33)(H,29,31)(H,30,32)
InChIKey QINPEPAQOBZPOF-UHFFFAOYSA-N
SMILES CC(C)(C(=O)NC1=CC(=CC=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=C(C=CC(=C4)OC)Cl)N
Reference

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[1]. Patent No: WO 2012065057&nbsp;
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[2]. Patent No: WO 2012006552
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