For research use only. Not for therapeutic Use.
WKYMVM-NH₂ TFA（Cat No.:I044761）is a synthetic hexapeptide (Trp-Lys-Tyr-Met-Val-Met-NH₂) supplied as a trifluoroacetate salt, known for its potent agonist activity at formyl peptide receptor-like 1 (FPRL1/FPR2). It is widely used in immunological research to study neutrophil activation, chemotaxis, and inflammatory signaling pathways. The C-terminal amide enhances peptide stability and receptor affinity. WKYMVM-NH₂ is particularly valuable for investigating innate immune responses, cellular migration, and receptor-mediated signaling cascades. Its high specificity makes it a key tool in elucidating FPR2-related functions in inflammation, host defense, and disease models.
| CAS Number | 1435781-74-0 |
| Synonyms | (2S)-6-amino-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]hexanamide;2,2,2-trifluoroacetic acid |
| Molecular Formula | C43H62F3N9O9S2 |
| Purity | ≥95% |
| IUPAC Name | (2S)-6-amino-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]hexanamide;2,2,2-trifluoroacetic acid |
| InChI | InChI=1S/C41H61N9O7S2.C2HF3O2/c1-24(2)35(41(57)46-31(36(44)52)16-19-58-3)50-39(55)33(17-20-59-4)48-40(56)34(21-25-12-14-27(51)15-13-25)49-38(54)32(11-7-8-18-42)47-37(53)29(43)22-26-23-45-30-10-6-5-9-28(26)30;3-2(4,5)1(6)7/h5-6,9-10,12-15,23-24,29,31-35,45,51H,7-8,11,16-22,42-43H2,1-4H3,(H2,44,52)(H,46,57)(H,47,53)(H,48,56)(H,49,54)(H,50,55);(H,6,7)/t29-,31-,32-,33-,34-,35-;/m0./s1 |
| InChIKey | MYVYQWVNXDVTBW-CZPFDPCBSA-N |
| SMILES | CC(C)[C@@H](C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)N.C(=O)(C(F)(F)F)O |
| Reference |
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| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
