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Withanolide A

Withanolide A

  • CAT Number: R020844
  • CAS Number: 32911-62-9
  • Molecular Formula: C28H38O6
  • Molecular Weight: 470.606
  • Purity: ≥95%
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Withanolide A is a natural product isolated from the medicinal plant <em>W. somnifera</em> that has antioxidant and neuroprotective activity. It helps to promote neurite outgrowth at 1 µM in cultured neurons and in rodents injected with Aβ(25-35), and also recovers Aβ(25-35)-induced memory deficit in mice (10 µmol/kg/day). Withanolide A reverses hypoxia-mediated neurodegeneration by restoring hypoxia-induced glutathione depletion in the hippocampus of mice.

Catalog Number R020844
CAS Number 32911-62-9
Molecular Formula

C28H38O6

Purity 95%
Storage -20°C
InChI InChI=1S/C28H38O6/c1-14-13-20(33-24(30)15(14)2)27(5,31)18-9-8-16-21-17(10-12-25(16,18)3)26(4)19(29)7-6-11-28(26,32)23-22(21)34-23/h6-7,16-18,20-23,31-32H,8-13H2,1-5H3/t16-,17-,18-,20+,21-,22-,23-,25-,26-,27+,28-/m0/s1
InChIKey DXWHOKCXBGLTMQ-SFQAJKIESA-N
SMILES CC1=C(C(=O)OC(C1)C(C)(C2CCC3C2(CCC4C3C5C(O5)C6(C4(C(=O)C=CC6)C)O)C)O)C

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