WHI-P154 - CAS 211555-04-3
WHI-P154 (Cat.No:I002626) is a promising small molecule inhibitor that has gained attention for its potential therapeutic applications. It specifically targets JAK3 and has shown efficacy in preclinical studies for various autoimmune and inflammatory diseases. Further research is ongoing to explore its clinical benefits and safety profile.
Catalog Number: I002626
CAS Number: 211555-04-3
PubChem Substance ID:355039494
Molecular Formula: C₁₆H₁₄BrN₃O₃
Molecular Weight:376.2
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Synonym
Synonyms | 2-bromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol |
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Property
Molecular Formula: | C₁₆H₁₄BrN₃O₃ |
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Molecular Weight | 376.2 |
Target: | JAK |
Solubility | DMSO: ≥ 47 mg/mL |
Purity | ≥95% |
Storage | 3 years -20℃ powder |
IC50 | 1.8 uM (JAK3); 4 nM(EGFR);100 nM(VEGFR) [1] |
Computed Descriptor
IUPAC Name | 2-bromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol |
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InChI | InChI=1S/C16H14BrN3O3/c1-22-14-6-10-12(7-15(14)23-2)18-8-19-16(10)20-9-3-4-13(21)11(17)5-9/h3-8,21H,1-2H3,(H,18,19,20) |
InChIKey | CBIAKDAYHRWZCU-UHFFFAOYSA-N |
SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC |