For research use only. Not for therapeutic Use.
3-[(5Z)-5-[(2-ethoxynaphthalen-1-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid(CAT: I040598) is a thiazolidinone-based selective cyclooxygenase-2 (COX-2) inhibitor designed to reduce inflammation with minimal gastrointestinal toxicity. Its unique structure includes a naphthalene ring and propanoic acid side chain, promoting high COX-2 binding affinity while sparing COX-1. This compound effectively downregulates prostaglandin synthesis, making it ideal for use in preclinical studies of inflammatory diseases, arthritis, and cancer-related inflammation. It serves as a promising lead for drug development or as a biochemical tool in mechanistic studies of COX-2 signaling pathways. Suitable for both in vitro assays and in vivo pharmacological evaluations.
| CAS Number | 728924-73-0 |
| Synonyms | 3-[(5Z)-5-[(2-ethoxynaphthalen-1-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid |
| Molecular Formula | C19H17NO4S2 |
| Purity | ≥95% |
| IUPAC Name | 3-[(5Z)-5-[(2-ethoxynaphthalen-1-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid |
| InChI | InChI=1S/C19H17NO4S2/c1-2-24-15-8-7-12-5-3-4-6-13(12)14(15)11-16-18(23)20(19(25)26-16)10-9-17(21)22/h3-8,11H,2,9-10H2,1H3,(H,21,22)/b16-11- |
| InChIKey | VRQDQAOHZIBDSQ-WJDWOHSUSA-N |
| SMILES | CCOC1=C(C2=CC=CC=C2C=C1)C=C3C(=O)N(C(=S)S3)CCC(=O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
