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KUN29943

KUN29943

  • CAT Number: I030194
  • CAS Number: 425629-94-3
  • Molecular Formula: C13H12ClNO3S
  • Molecular Weight: 297.753
  • Purity: 98%
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KUN29943(CAT: I030194) is a specific inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH). PfDHODH is an enzyme involved in the de novo pyrimidine biosynthesis pathway of the malaria parasite Plasmodium falciparum. By inhibiting PfDHODH, KUN29943 disrupts the production of pyrimidines, essential components for DNA and RNA synthesis in the parasite, thereby inhibiting its growth and proliferation. KUN29943’s inhibition of PfDHODH makes it a potential target for the development of new antimalarial drugs.

Catalog Number I030194
CAS Number 425629-94-3
Molecular Formula

C13H12ClNO3S

Purity 98
Solubility To be determined
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name ethyl 2-((4-chlorophenyl)amino)-4-oxo-4,5-dihydrothiophene-3-carboxylate
InChI InChI=1S/C13H12ClNO3S/c1-2-18-13(17)11-10(16)7-19-12(11)15-9-5-3-8(14)4-6-9/h3-6,15H,2,7H2,1H3
InChIKey KJEPGRNXDUXOLD-UHFFFAOYSA-N
SMILES O=C(C1=C(NC2=CC=C(Cl)C=C2)SCC1=O)OCC

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