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VUF 10460

VUF 10460

  • CAT Number: I011024
  • CAS Number: 1028327-66-3
  • Molecular Formula: C15H19N5
  • Molecular Weight: 269.34
  • Purity: ≥95%
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VUF10460 is a small molecule compound that acts as an agonist for the histamine H4 receptor. It has been shown to selectively activate H4 receptors, which are involved in various physiological and pathological processes, such as inflammation, immune responses, and pruritus. VUF10460 has been studied for its potential therapeutic use in various conditions, such as allergies, asthma, and autoimmune diseases.

Catalog Number I011024
CAS Number 1028327-66-3
Molecular Formula

C15H19N5

Purity 95%
Target Histamine Receptor
Solubility Soluble to 100 mM in DMSO and to 100 mM in 2eq.HCl
Storage 2–8 °C
IUPAC Name 4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine
InChI InChI=1S/C15H19N5/c1-19-7-9-20(10-8-19)14-11-13(17-15(16)18-14)12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3,(H2,16,17,18)
InChIKey NIJGWJIOMPHDBP-UHFFFAOYSA-N
SMILES CN1CCN(CC1)C2=NC(=NC(=C2)C3=CC=CC=C3)N

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