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VU 0364739 hydrochloride

VU 0364739 hydrochloride

  • CAT Number: I010903
  • CAS Number: 1244640-48-9
  • Molecular Formula: C26H28ClFN4O2
  • Molecular Weight: 482.984
  • Purity: ≥95%
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VU 0364739 hydrochloride (Cat.No:I010903) is a potent and selective phospholipase D2 (PLD2) inhibitor (IC<sub>50</sub> = 20 nM); displays 75-fold selectivity against PLD1 (IC<sub>50</sub> = 1500 nM).

Catalog Number I010903
CAS Number 1244640-48-9
Molecular Formula

C26H28ClFN4O2

Purity 95%
Target Phospholipase
Solubility Soluble to 100 mM in DMSO
Storage Desiccate at RT
IUPAC Name N-[2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]naphthalene-2-carboxamide;hydrochloride
InChI InChI=1S/C26H27FN4O2.ClH/c27-22-6-3-7-23(17-22)31-18-29-25(33)26(31)10-13-30(14-11-26)15-12-28-24(32)21-9-8-19-4-1-2-5-20(19)16-21;/h1-9,16-17H,10-15,18H2,(H,28,32)(H,29,33);1H
InChIKey RYLAMDMOILNBKN-UHFFFAOYSA-N
SMILES C1CN(CCC12C(=O)NCN2C3=CC(=CC=C3)F)CCNC(=O)C4=CC5=CC=CC=C5C=C4.Cl

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