VRT752271

  • CAT Number: I005233
  • CAS Number: 869886-67-9
  • Molecular Formula: C₂₁H₂₂Cl₂N₄O₂
  • Molecular Weight: 433.33
  • Purity: ≥95%
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VRT752271(CAT: I005233) is a small molecule inhibitor that targets the extracellular signal-regulated kinase (ERK) protein kinase pathway. By binding to ERK, VRT752271 interferes with the activation and signaling of this kinase. The ERK pathway is a key signaling cascade involved in cell proliferation, differentiation, and survival. Inhibition of ERK can potentially disrupt the growth and survival of cancer cells and may have therapeutic implications for various diseases, including cancer.

Catalog Number I005233
CAS Number 869886-67-9
Molecular Formula

C₂₁H₂₂Cl₂N₄O₂

Purity 95%
Target ERK
Solubility DMSO: ≥ 45 mg/mL
Storage Store at -20C
InChI InChI=1S/C21H22Cl2N4O2/c1-12(2)26-20-8-16(17(23)10-25-20)14-7-18(24-9-14)21(29)27-19(11-28)13-4-3-5-15(22)6-13/h3-10,12,19,24,28H,11H2,1-2H3,(H,25,26)(H,27,29)/t19-/m1/s1
InChIKey KSERXGMCDHOLSS-LJQANCHMSA-N
SMILES CC(C)NC1=NC=C(C(=C1)C2=CNC(=C2)C(=O)NC(CO)C3=CC(=CC=C3)Cl)Cl
Reference

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