Vitamin D4

• CAT Number: I003831
• CAS Number: 511-28-4
• Molecular Formula: C28H46O
• Molecular Weight: 398.66
• Purity: ≥95%
• Synonyms: (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5S)-5,6-dimethylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol
• Target: VD/VDR
• Solubility: 10 mM in DMSO
• Storage: 2-8°C
• InChI: InChI=1S/C28H46O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h12-13,19-20,22,25-27,29H,4,7-11,14-18H2,1-3,5-6H3/b23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1
• InChIKey: DIPPFEXMRDPFBK-JPWDPSJFSA-N
• SMILES: CC(C)C(C)CCC(C)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C

Vitamin D4 (Cat.No:I003831), also known as 22-dihydroergocalciferol (CAS 511-28-4), is a lesser-known variant of Vitamin D. It shares similarities with Vitamin D2 in its structure and biological activity. However, its presence in the human body and dietary sources are limited compared to other forms of Vitamin D. Further research is needed to explore its potential health benefits.

Reference

[1]. Byford V, et al. Use of vitamin D(4) analogs to investigate differences in hepatic and target cell metabolism of vitamins D(2) and D(3). Biochim Biophys Acta. 2002 Jul 11;1583(2):151-66.
[2]. Tachibana Y, Tsuji M. Study on the metabolites of 1alpha,25-dihydroxyvitamin D4. Steroids. 2001 Feb;66(2):93-97.
[3]. Tsugawa N, et al. Biological activity profiles of 1alpha,25-dihydroxyvitamin D2, D3, D4, D7, and 24-epi-1alpha,25-dihydroxyvitamin D2. Biol Pharm Bull. 1999 Apr;22(4):371-7.
[4]. Rikkers H, DeLuca H, Lobeck C. Metabolism and serum protein binding of 3H-vitamin D4 in vitamin D-resistant rickets. J Pediatr. 1969 May;74(5):828.
[5]. De Luca HF, Weller M, Blunt JW, Neville PF. Synthesis, biological activity., and metabolism of 22,23-3H vitamin D4. Arch Biochem Biophys. 1968 Mar 20;124(1):122-8.