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VII-31

VII-31

  • CAT Number: I015275
  • CAS Number: 2305757-96-2
  • Molecular Formula: C₂₃H₂₅NO₅S
  • Molecular Weight: 427.51
  • Purity: ≥95%
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VII-31（Cat No.:I015275） is a compound with high potency to activate the NEDDylation pathway and inhibit tumor progression in both in vitro and in vivo studies. The compound is capable of inducing apoptosis through intrinsic and extrinsic pathways.

Catalog Number I015275
CAS Number 2305757-96-2
Molecular Formula

C₂₃H₂₅NO₅S

Purity 95%
IUPAC Name N-[(4-methoxyphenyl)methyl]-2-thiophen-2-yl-N-(3,4,5-trimethoxyphenyl)acetamide
InChI InChI=1S/C23H25NO5S/c1-26-18-9-7-16(8-10-18)15-24(22(25)14-19-6-5-11-30-19)17-12-20(27-2)23(29-4)21(13-17)28-3/h5-13H,14-15H2,1-4H3
InChIKey CGVFRZMQURRQIE-UHFFFAOYSA-N
SMILES COC1=CC=C(C=C1)CN(C2=CC(=C(C(=C2)OC)OC)OC)C(=O)CC3=CC=CS3
Reference

[1]. Dong-Jun Fu, et al. Discovery of Novel Tertiary Amide Derivatives as NEDDylation Pathway Activators to Inhibit the Tumor Progression in Vitro and in Vivo. Eur J Med Chem. 2020 Apr 15;192:112153.

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