CONTACT US
Home > Inhibitors/Agonists> > Vatalanib succinate
Vatalanib succinate

Vatalanib succinate

  • CAT Number: I011272
  • CAS Number: 212142-18-2
  • Molecular Formula: C24H21ClN4O4
  • Molecular Weight: 464.906
  • Purity: ≥95%
Inquiry Now

Potent VEGFR inhibitor (IC<sub>50</sub> values are 37 and 77 nM for VEGFR-2 and -1, respectively). Inhibits proliferation, migration and survival of HUVECs <em>in vitro</em> and inhibits growth, vascularization and metastasis of tumors expressing VEGFR in mouse models. Also inhibits PDGFR-<span class=/’symbol/’>&#946;</span>, c-Kit and c-Fms. Potent aromatase inhibitor (IC<sub>50</sub> = 50 nM). Orally available.

Catalog Number I011272
CAS Number 212142-18-2
Synonyms

Alternative Names: CGP 79787D, PTK787/ZK222584

Molecular Formula

C24H21ClN4O4

Purity 95%
Solubility Soluble to 100 mM in DMSO
Storage Store at -20C
IUPAC Name butanedioic acid;N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
InChI InChI=1S/C20H15ClN4.C4H6O4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;5-3(6)1-2-4(7)8/h1-12H,13H2,(H,23,25);1-2H2,(H,5,6)(H,7,8)
InChIKey LLDWLPRYLVPDTG-UHFFFAOYSA-N
SMILES C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.C(CC(=O)O)C(=O)O

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!