Valdecoxib

• CAT Number: A000619
• CAS Number: 181695-72-7
• Molecular Formula: C₁₆H₁₄N₂O₃S
• Molecular Weight: 314.36
• Purity: ≥95%
• Synonyms: 181695-72-7; Bextra; 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide; 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide; Valdyn
• Target: Metabolic Enzyme/Protease
• Solubility: Soluble in DMSO > 10 mM
• Storage: -20°C
• InChI: InChI=1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20)
• InChIKey: LNPDTQAFDNKSHK-UHFFFAOYSA-N
• SMILES: CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N

Valdecoxib, also known as SC-65872, is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is a selective cyclooxygenase-2 inhibitor. It was approved in 2001 to treat arthritis and menstrual cramps. It was withdraw in 2005.

Reference

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