Val-cit-PAB-OH

• CAT Number: I002027
• CAS Number: 159857-79-1
• Molecular Formula: C18H29N5O4
• Molecular Weight: 379.45
• Purity: ≥95%
• Solubility: DMSO: ≥ 59 mg/mL
• Storage: 2-8°C(protect from light)
• IUPAC Name: (2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)-N-[4-(hydroxymethyl)phenyl]pentanamide
• InChI: InChI=1S/C18H29N5O4/c1-11(2)15(19)17(26)23-14(4-3-9-21-18(20)27)16(25)22-13-7-5-12(10-24)6-8-13/h5-8,11,14-15,24H,3-4,9-10,19H2,1-2H3,(H,22,25)(H,23,26)(H3,20,21,27)/t14-,15-/m0/s1
• InChIKey: VEGGTWZUZGZKHY-GJZGRUSLSA-N
• SMILES: CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)N

Val-cit-PAB-OH (Cat No.: I002027) is a degradable antibody-drug conjugate (ADC) linker with diverse applications. It serves as a crucial reagent in the preparation of cell-penetrating peptide GRP78 ligands for targeted prodrug therapy in tumor cells. Additionally, it plays a pivotal role in the development of ligands and antibodies derived from monomethyl valine, contributing to innovative cancer treatment approaches. Researchers interested in utilizing Val-cit-PAB-OH for these purposes or seeking further information can contact us for support.