Uridine diphosphate glucose

• CAT Number: M070868
• CAS Number: 133-89-1
• Molecular Formula: C15H24N2O17P2
• Molecular Weight: 566.302
• Purity: ≥95%
• Storage: -20°C
• Related CAS: 28053-08-9(sodium salt)
• IUPAC Name: [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
• InChI: InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
• InChIKey: HSCJRCZFDFQWRP-JZMIEXBBSA-N
• SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OC3C(C(C(C(O3)CO)O)O)O)O)O

Uridine diphosphate glucose(CAS 133-89-1) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine diphosphate glucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR.

Reference

1.Führing, Jana Indra, et al. "A quaternary mechanism enables the complex biological functions of octameric human UDP-glucose pyrophosphorylase, a key enzyme in cell metabolism." Scientific reports 5.1 (2015): 1-11.
2.Wahlefeld, A. W., and H. U. Bergmeyer. "Methods of enzymatic analysis." Triglycerides determination after enzymatic hydrolysis. 2nd English ed., Academic Press, Inc, New York (1974): 18-31.
3.Das, Arijit, et al. "Human P2Y14 receptor agonists: truncation of the hexose moiety of uridine-5′-diphosphoglucose and its replacement with alkyl and aryl groups." Journal of medicinal chemistry 53.1 (2010): 471-480.