UCB-6786

  • CAT Number: I037763
  • CAS Number: 537018-21-6
  • Molecular Formula: C16H16N2O
  • Molecular Weight: 252.317
  • Purity: 98%
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UCB-6786 (CAT: I037763) is a novel inhibitor of tumor necrosis factor (TNF) signaling. It exerts its inhibitory effects by stabilizing an asymmetric form of the TNF trimer. UCB-6786 displays a concentration-dependent response curve and exhibits selectivity over the extracellular domain of TNF receptor 1 (TNFR1) and control proteins. By targeting TNF signaling, UCB-6786 has the potential to modulate inflammatory responses and may have therapeutic applications in diseases associated with dysregulated TNF signaling pathways.

Catalog Number I037763
CAS Number 537018-21-6
Synonyms

UCB-6786; UCB 6786; UCB6786

Molecular Formula

C16H16N2O

Purity 98
Solubility Soluble in DMSO
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name (1-(2-Methylbenzyl)-1H-benzo[d]imidazol-2-yl)methanol
InChI InChI=1S/C16H16N2O/c1-12-6-2-3-7-13(12)10-18-15-9-5-4-8-14(15)17-16(18)11-19/h2-9,19H,10-11H2,1H3
InChIKey FDWSLDWZHYNDAX-UHFFFAOYSA-N
SMILES OCC1=NC2=CC=CC=C2N1CC3=CC=CC=C3C

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