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UCB-6786 - CAS 537018-21-6

UCB-6786 (CAT: I037763) is a novel inhibitor of tumor necrosis factor (TNF) signaling. It exerts its inhibitory effects by stabilizing an asymmetric form of the TNF trimer. UCB-6786 displays a concentration-dependent response curve and exhibits selectivity over the extracellular domain of TNF receptor 1 (TNFR1) and control proteins. By targeting TNF signaling, UCB-6786 has the potential to modulate inflammatory responses and may have therapeutic applications in diseases associated with dysregulated TNF signaling pathways.

Catalog Number: I037763

CAS Number: 537018-21-6

Molecular Formula: C16H16N2O

Molecular Weight:252.317

Purity: 98.0%

Appearance:Solid powder

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Synonym

SynonymsUCB-6786; UCB 6786; UCB6786

Property

Molecular Formula: C16H16N2O
Molecular Weight252.317
SolubilitySoluble in DMSO
Purity98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Computed Descriptor

IUPAC Name(1-(2-Methylbenzyl)-1H-benzo[d]imidazol-2-yl)methanol
InChIInChI=1S/C16H16N2O/c1-12-6-2-3-7-13(12)10-18-15-9-5-4-8-14(15)17-16(18)11-19/h2-9,19H,10-11H2,1H3
InChIKeyFDWSLDWZHYNDAX-UHFFFAOYSA-N
SMILESOCC1=NC2=CC=CC=C2N1CC3=CC=CC=C3C