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U-75302

U-75302

  • CAT Number: R067354
  • CAS Number: 119477-85-9
  • Molecular Formula: C22H35NO3
  • Molecular Weight: 361.5
  • Purity: ≥95%
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U-<wbr></wbr>75302 is an LTB<sub>4</sub> receptor antagonist with a K<sub>i</sub> of 159 nM on guinea pig lung membranes. This activity is specific for the BLT<sub>1</sub> receptor; U-<wbr></wbr>75302 does not antagonize the binding of [

Catalog Number R067354
CAS Number 119477-85-9
Molecular Formula

C22H35NO3

Purity 95%
Storage -20°C
InChI InChI=1S/C22H35NO3/c1-2-3-4-5-6-7-13-21(25)16-15-19-11-10-12-20(23-19)18-22(26)14-8-9-17-24/h6-7,10-12,15-16,21-22,24-26H,2-5,8-9,13-14,17-18H2,1H3/b7-6-,16-15+/t21-,22+/m1/s1
InChIKey JNBOAUIJLDEICX-LJCAKPRGSA-N
SMILES OCCCC[C@H](O)CC1=NC(/C=C/[C@H](O)C/C=CCCCCC)=CC=C1
Reference

1.Falcone, R.C., and Aharony, D. Modulation of ligand binding to leukotriene B4 receptors on guinea pig lung membranes by sulfhydryl modifying reagents. Journal of Pharmacology and Experimental Therapeutics 255, 565-571 (1990).

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