TRIS(4-AMINOPHENYL)METHANE

• CAT Number: M000286
• CAS Number: 548-61-8
• Molecular Formula: C19H19N3
• Molecular Weight: 289.382
• Purity: ≥95%
• Storage: RT
• IUPAC Name: 4-[bis(4-aminophenyl)methyl]aniline
• InChI: InChI=1S/C19H19N3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,19H,20-22H2
• InChIKey: ADUMIBSPEHFSLA-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C(C2=CC=C(C=C2)N)C3=CC=C(C=C3)N)N

TRIS(4-AMINOPHENYL)METHANE (CAS 548-61-8) is a triphenylmethane dye. It is a weak HCV helicase inhibitor,
showing weak HCV helicase inhibition (30% inhibition at 100 μM). It can be used to preserve RNA in a biological sample for analysis. RNA preservation may be used in an immunostaining assay and other histochemical methods.

Reference

1. Chen CS, et al. Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virushelicase. J Med Chem. 2009 May 14;52(9):2716-23.
2.Kamme, Fredrik C., et al. "Preservation of RNA in a biological sample." U.S. Patent No. 7,056,673. 6 Jun. 2006.