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Triclabendazole

Triclabendazole

  • CAT Number: A000387
  • CAS Number: 68786-66-3
  • Molecular Formula: C14H9Cl3N2OS
  • Molecular Weight: 359.7
  • Purity: ≥95%
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Triclabendazole is a member of the benzimidazole family of anthelmintics. It is effective against <em>F. hepatica</em> helminths that cause fascioliasis, reducing secreted protease enzyme activities that are critical for the invasion, migration, nutrition, and survival of the parasite. In yeast and mammalian cells, triclabendazole was shown to inhibit adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A nutrient-sensing pathway and to prevent apoptosis induced by the Parkinson’s disease-related protein α-synuclein, demonstrating a protective role during various cellular stresses.

Catalog Number A000387
CAS Number 68786-66-3
Synonyms

CGA-89317

Molecular Formula

C14H9Cl3N2OS

Purity 95%
Storage -20°C
InChIKey NQPDXQQQCQDHHW-UHFFFAOYSA-N

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