Trichlormethiazide

• CAT Number: A000756
• CAS Number: 133-67-5
• Molecular Formula: C8H8Cl3N3O4S2
• Molecular Weight: 380.66
• Purity: ≥95%
• Storage: -20°C
• InChI: 1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
• InChIKey: LMJSLTNSBFUCMU-UHFFFAOYSA-N
• SMILES: C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)NC(N2)C(Cl)Cl

Trichlormethiazide is a diuretic with properties similar to those of hydrochlorothiazide. It is usually administered for the treatment of oedema (including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy) and hypertension. In veterinary medicine, trichlormethiazide can be combined with dexamethasone to be used on horses with mild swelling of distal limbs and general bruising. As a diuretic (in particular a thiazide), trichlormethiazide encourages water loss from the body.

Reference

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