Tranylcypromine Hemisulfate

• CAT Number: I001341
• CAS Number: 13492-01-8
• Molecular Formula: C₉H₁₁N.1/2H₂SO₄
• Molecular Weight: 182.2
• Purity: ≥95%
• Solubility: H2O: 25 mg/mL
• Storage: Store at -20°C
• InChI: InChI=1S/C9H11N.H2O4S/c10-9-6-8(9)7-4-2-1-3-5-7;1-5(2,3)4/h1-5,8-9H,6,10H2;(H2,1,2,3,4)/t8-,9+;/m0./s1
• InChIKey: BTHVHSMCHJCPFU-OULXEKPRSA-N
• SMILES: C1C(C1N)C2=CC=CC=C2.OS(=O)(=O)O

Tranylcypromine hemisulfate is an inhibitor of monoamine oxidase (MAO) and prostacyclin synthase, potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 <2 μM for BHC110/LSD1).

Reference

[1]. Caraci F, et al. Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity. Eur J Pharmacol. 2015 Oct 5;764:256-263.