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Tos-PEG4-NH-Boc

Tos-PEG4-NH-Boc

  • CAT Number: I018636
  • CAS Number: 1246999-33-6
  • Molecular Formula: C₂₀H₃₃NO₈S
  • Molecular Weight: 447.54
  • Purity: ≥95%
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Tos-PEG4-NH-Boc (CAT: I018636) is a PEG-based PROTAC linker, specifically designed for use in the synthesis of PROTACs. PROTACs (PROteolysis TArgeting Chimeras) are innovative molecules that work by harnessing the cell’s own machinery to selectively degrade target proteins within cells. The linker plays a crucial role in connecting the target protein binder (ligand) and the E3 ubiquitin ligase recruiting moiety, facilitating the targeted protein degradation process.

Catalog Number I018636
CAS Number 1246999-33-6
Molecular Formula

C₂₀H₃₃NO₈S

Purity 95%
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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