Tolnaftate

• CAT Number: A000494
• CAS Number: 2398-96-1
• Molecular Formula: C19H17NOS
• Molecular Weight: 307.4
• Purity: ≥95%
• Storage: -20°C
• InChI: 1S/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3
• InChIKey: FUSNMLFNXJSCDI-UHFFFAOYSA-N
• SMILES: CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2

Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent that may be sold without medical prescription in most jurisdictions. It can be administered as a cream, powder, spray, and liquid aerosol. Tolnaftate is used to treat fungal conditions such as jock itch, athlete/’s foot and ringworm.

Reference

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6: Tang B, Wang X, Wang G, Yu C, Chen Z. Highly sensitive and selective
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inclusion complex of beta-naphthol/beta-cyclodextrin/anionic surfactant system.
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7: Bo T, Xu W, Jing W, Chengguang Y, Zhenzhen C, Yi D. Study on the
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beta-naphthol/beta-cyclodextrin/anionic surfactant in a tolnaftate hydrolysis
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8: Czeizel AE, Kazy Z, Puhó E. Tolnaftate spray treatment during pregnancy.
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9: Yamaguchi H, Uchida K, Tanaka T, Yamaguchi T. [Therapeutic efficacy of a
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