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TMPH hydrochloride

TMPH hydrochloride

  • CAT Number: I010553
  • CAS Number: 849461-91-2
  • Molecular Formula: C16H32ClNO2
  • Molecular Weight: 305.887
  • Purity: ≥95%
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Potent non-competitive antagonist of neuronal nicotinic ACh receptors (nAChRs). Produces long-lasting inhibition of neuronal nAChRs formed by the combination of the most abundant <span class=/’symbol/’>&alpha;</span> and <span class=/’symbol/’>&beta;</span> subunits (i.e. <span class=/’symbol/’>&alpha;</span>3, <span class=/’symbol/’>&alpha;</span>4 and <span class=/’symbol/’>&beta;</span>2, <span class=/’symbol/’>&beta;</span>4 respectively). Displays little inhibition of muscle-type (<span class=/’symbol/’>&alpha;</span>1<span class=/’symbol/’>&beta;</span>1<span class=/’symbol/’>&gamma;</span><span class=/’symbol/’>&delta;</span>) or <span class=/’symbol/’>&alpha;</span>7 receptors.

Catalog Number I010553
CAS Number 849461-91-2
Molecular Formula

C16H32ClNO2

Purity 95%
Target Nicotinic Receptor
Solubility Soluble to 100 mM in water and to 100 mM in DMSO
Storage Desiccate at RT
IUPAC Name (2,2,6,6-tetramethylpiperidin-4-yl) heptanoate;hydrochloride
InChI InChI=1S/C16H31NO2.ClH/c1-6-7-8-9-10-14(18)19-13-11-15(2,3)17-16(4,5)12-13;/h13,17H,6-12H2,1-5H3;1H
InChIKey XIDDVJIJIFWGIX-UHFFFAOYSA-N
SMILES CCCCCCC(=O)OC1CC(NC(C1)(C)C)(C)C.Cl

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