Tildipirosin - CAS 328898-40-4
Tildipirosin(Cat No.:I003170), commercially known as Zuprevo, is a newly developed 16-membered macrolide antibiotic primarily used for the treatment, control, and prevention of bovine respiratory disease in cattle. It exerts its antimicrobial effects by inhibiting protein synthesis on the ribosome, with an IC50 value of 0.23 ± 0.01 μM. The unique structure of tildipirosin contributes to its enhanced efficacy against respiratory pathogens commonly associated with bovine respiratory disease.
Catalog Number: I003170
CAS Number: 328898-40-4
PubChem Substance ID:355038984
Molecular Formula: C₄₁H₇₁N₃O₈
Molecular Weight:734.03
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Synonym
Synonyms | 20-deoxo-23-deoxy-5-O-[3,6-dideoxy-3-(dimethylamino)-β-D-glucopyranosyl]-20,23-di-1-piperidinyl-tylonolide |
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Property
Molecular Formula: | C₄₁H₇₁N₃O₈ |
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Molecular Weight | 734.03 |
Target: | Antibiotic; Protein synthesis inhibitor |
Solubility | 10 mM in DMSO |
Purity | ≥95% |
Storage | 2-8°C |
Computed Descriptor
IUPAC Name | (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-5,9,13-trimethyl-7-(2-piperidin-1-ylethyl)-15-(piperidin-1-ylmethyl)-1-oxacyclohexadeca-11,13-diene-2,10-dione |
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InChI | InChI=1S/C41H71N3O8/c1-8-35-32(26-44-20-13-10-14-21-44)23-27(2)15-16-33(45)28(3)24-31(17-22-43-18-11-9-12-19-43)40(29(4)34(46)25-36(47)51-35)52-41-39(49)37(42(6)7)38(48)30(5)50-41/h15-16,23,28-32,34-35,37-41,46,48-49H,8-14,17-22,24-26H2,1-7H3/b16-15+,27-23+/t28-,29+,30-,31+,32-,34-,35-,37+,38-,39-,40-,41+/m1/s1 |
InChIKey | HNDXPZPJZGTJLJ-UEJFNEDBSA-N |
SMILES | CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)O)N(C)C)O)CCN3CCCCC3)C)C)CN4CCCCC4 |