Tildipirosin - CAS 328898-40-4

Tildipirosin(Cat No.:I003170), commercially known as Zuprevo, is a newly developed 16-membered macrolide antibiotic primarily used for the treatment, control, and prevention of bovine respiratory disease in cattle. It exerts its antimicrobial effects by inhibiting protein synthesis on the ribosome, with an IC50 value of 0.23 ± 0.01 μM. The unique structure of tildipirosin contributes to its enhanced efficacy against respiratory pathogens commonly associated with bovine respiratory disease.

Catalog Number: I003170

CAS Number: 328898-40-4

PubChem Substance ID:355038984

Molecular Formula: C₄₁H₇₁N₃O₈

Molecular Weight:734.03

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

Synonyms20-deoxo-23-deoxy-5-O-[3,6-dideoxy-3-(dimethylamino)-β-D-glucopyranosyl]-20,23-di-1-piperidinyl-tylonolide

Property

Molecular Formula: C₄₁H₇₁N₃O₈
Molecular Weight734.03
Target:Antibiotic; Protein synthesis inhibitor
Solubility10 mM in DMSO
Purity≥95%
Storage2-8°C

Computed Descriptor

IUPAC Name(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-5,9,13-trimethyl-7-(2-piperidin-1-ylethyl)-15-(piperidin-1-ylmethyl)-1-oxacyclohexadeca-11,13-diene-2,10-dione
InChIInChI=1S/C41H71N3O8/c1-8-35-32(26-44-20-13-10-14-21-44)23-27(2)15-16-33(45)28(3)24-31(17-22-43-18-11-9-12-19-43)40(29(4)34(46)25-36(47)51-35)52-41-39(49)37(42(6)7)38(48)30(5)50-41/h15-16,23,28-32,34-35,37-41,46,48-49H,8-14,17-22,24-26H2,1-7H3/b16-15+,27-23+/t28-,29+,30-,31+,32-,34-,35-,37+,38-,39-,40-,41+/m1/s1
InChIKeyHNDXPZPJZGTJLJ-UEJFNEDBSA-N
SMILESCCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)O)N(C)C)O)CCN3CCCCC3)C)C)CN4CCCCC4