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THP-PEG6-OH

THP-PEG6-OH

  • CAT Number: I017124
  • CAS Number: 42607-87-4
  • Molecular Formula: C₁₇H₃₄O₈
  • Molecular Weight: 366.45
  • Purity: ≥95%
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THP-PEG6-OH (Cat No.:I017124) is a PROTAClinker belonging to the PEG class. THP-PEG6-OH can be used to synthesize PROTAC molecules. THP-PEG6-OH is also a non-cleavable ADClinker containing 6 units of PEG, which can be used to synthesize antibody drug conjugates (ADC).

Catalog Number I017124
CAS Number 42607-87-4
Molecular Formula

C₁₇H₃₄O₈

Purity 95%
IUPAC Name 2-[2-[2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
InChI InChI=1S/C17H34O8/c18-4-6-19-7-8-20-9-10-21-11-12-22-13-14-23-15-16-25-17-3-1-2-5-24-17/h17-18H,1-16H2
InChIKey ABJWCLPYMPRGRB-UHFFFAOYSA-N
SMILES C1CCOC(C1)OCCOCCOCCOCCOCCOCCO
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.<br>[2]. Masahiro Tomita, et al. Antibody specifically recognizing resin plasticizer compound. WO2005105846A1.

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