Thio-TEPA

• CAT Number: I003904
• CAS Number: 52-24-4
• Molecular Formula: C6H12N3PS
• Molecular Weight: 189.22
• Purity: ≥95%
• Target: DNA Alkylating
• Solubility: 10 mM in DMSO
• Storage: 2-8°C
• IUPAC Name: tris(aziridin-1-yl)-sulfanylidene-λ5-phosphane
• InChI: InChI=1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2
• InChIKey: FOCVUCIESVLUNU-UHFFFAOYSA-N
• SMILES: C1CN1P(=S)(N2CC2)N3CC3

Thio-TEPA（Cat No.:I003904）, also known as Thioplex or Tiofosfamid, is an alkylating agent primarily used in the treatment of cancer. This molecule possesses a tetrahedral phosphorus structure and is structurally similar to phosphate compounds. Thio-TEPA works by binding to DNA and interfering with its replication, ultimately leading to the destruction of cancer cells. It is commonly utilized in chemotherapy regimens for various cancers, including ovarian, breast, and bladder cancer. Thio-TEPA’s alkylating properties and structural resemblance to phosphate make it an effective tool in cancer treatment.

Reference

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