Thalidomide-5-NH₂-CH₂-COOH（Cat No.:I045038）is a functionalized derivative of thalidomide featuring an aminoacetic acid (glycine-like) moiety at the 5-position of the phthalimide ring. This modification introduces both an amino group and a carboxylic acid, enabling versatile conjugation to other molecules, such as linkers or payloads in targeted drug delivery systems, including PROTACs (proteolysis-targeting chimeras). While retaining thalidomide’s core structure—known for immunomodulatory and anti-angiogenic properties—this derivative is primarily used in medicinal chemistry and chemical biology for synthesizing bifunctional molecules aimed at modulating protein degradation or therapeutic targeting. Suitable for advanced drug design applications.