• CAT Number: I019813
  • CAS Number: 1011244-68-0
  • Molecular Formula: C₁₃H₁₀F₃N₃O
  • Molecular Weight: 281.23
  • Purity: ≥95%
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TFAP (CAT: I019813) is a selective inhibitor of cyclooxygenase-1 (COX-1). COX-1 is an enzyme involved in the production of prostaglandins, which play important roles in inflammation, pain, and other physiological processes. By selectively inhibiting COX-1, TFAP interferes with the synthesis of prostaglandins derived from arachidonic acid, leading to reduced inflammation and pain. This selective inhibition of COX-1 distinguishes TFAP from non-selective COX inhibitors, potentially minimizing unwanted side effects associated with COX-2 inhibition. TFAP’s selective COX-1 inhibitory activity may have therapeutic applications in conditions such as arthritis, cardiovascular diseases, and other inflammatory disorders.

Catalog Number I019813
CAS Number 1011244-68-0
Molecular Formula


Purity 95%

[1]. Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1840-3.

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