Tetrahydropalmatine

• CAT Number: I003021
• CAS Number: 2934-97-6
• Molecular Formula: C21H25NO4
• Molecular Weight: 355.43
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
• InChI: InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3
• InChIKey: AEQDJSLRWYMAQI-UHFFFAOYSA-N
• SMILES: COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC

Tetrahydropalmatine (Cat.No:I003021) is a natural alkaloid derived from the Chinese herb Corydalis yanhusuo. It has been used in traditional medicine for its analgesic and sedative properties. Tetrahydropalmatine is studied for its potential in treating substance addiction, neurological disorders, and pain management, but further research is needed to confirm its efficacy.

Reference

[1]. XING Shu-Hua, et al. Effects of dl-tetrahydropalmatine on blood pressure and norepinephrine and epinephrine contents in peripheral tissues. Acta Pharmacologica Sinica, 1994-01

[2]. C K, Chang, et al. DL-Tetrahydropalmatine may act through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats. Neuroscience letters, 2001, 307(3): 163-6

[3]. MIN Qing, et al. Protective effect of dl-tetrahydropalmatine on liver injury induced by carbon tetrachloride in mice. China Journal of Chinese Materia Medica, 2006-06

[4]. LIU Yu-mei, et al. Effects of dl-tetrahydropalmatine on potassium current in isolated myocytes of guinea pig. Chinese Pharmacological Bulletin,
2005-05