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Terutroban

Terutroban

  • CAT Number: I002164
  • CAS Number: 165538-40-9
  • Molecular Formula: C20H22ClNO4S
  • Molecular Weight: 407.9
  • Purity: ≥95%
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Terutroban (CAT: I002164) stands as a thromboxane/prostaglandin endoperoxide receptor antagonist. By acting on these receptors, Terutroban interferes with the binding of thromboxane and prostaglandin endoperoxide, which are involved in platelet aggregation and vasoconstriction. This pharmacologic action leads to antiplatelet and vasodilatory effects, making Terutroban valuable for managing cardiovascular conditions.

Catalog Number I002164
CAS Number 165538-40-9
Molecular Formula

C20H22ClNO4S

Purity 95%
Target Prostanoid Receptors
Solubility DMSO: ≥ 30 mg/mL
Storage Store at -20°C
InChIKey HWEOXFSBSQIWSY-MRXNPFEDSA-N
Reference

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<br>[1]. De La Cruz JP, et al. Effects of terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, on retinal vascularity in diabetic rats. Diabetes Metab Res Rev. 2012 Feb;28(2):132-138.
<br>[2]. Bots ML, et al. Thromboxane prostaglandin receptor antagonist and carotid atherosclerosis progression in patients with cerebrovascular disease of ischemic origin: a randomized controlled trial. Stroke. 2014 Aug;45(8):2348-2353.
<br>[3]. Lesault PF, et al. Daily administration of the TP receptor antagonist terutroban improved endothelial function in high-cardiovascular-risk patients with atherosclerosis. Br J Clin Pharmacol.2011 Jun;71(6):844-851.
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