<p>a neuronal nicotinic AChR antagonist. Potent ganglioblocker. Hypotensive. Good penetration of biological membranes. Secondary analog of Pempidol. Antioxidant, radical scavenger.</p><br />Piperidine derivative,<!–C9H19NO.HCl–>, synthetic.</br><p>For comparative information see the attached 2 tables. <br /><br /> Cell permeant central nicotinic cholinoreceptor blocker without action on skeleton muscle innervation.<br /><br /> Antioxidant (precursor of stable TEMPO nitroxyl radical): together with PEMPIDOL can be used for testing the possibility of antioxydant contribution into any observed biological activity of TEMPIDOL.<br /><br /> Potential antimitotic (ask for the TEMPIDONE data).</p></br>
| Catalog Number | T000144 |
| CAS Number | 24303-88-5 (base), 79316-86-2 (HCl). |
| Synonyms | 2,2,6,6-tetramethylpiperidinol-4 hydrochloride. |
| Molecular Formula | C9H19NO.HCl |
| Purity | 95% |
| Solubility | water, ethanol. |
| Storage | store at room temperature. Solution for use: dissolve in water: 10-3M (2 mg in 10.31 ml), stable for 1-2 days at 20C. |
| Reference | – Brehteric et al., <I>Nature</I> (1959). 184:1707-1709<br /><br /><br /><br /> |
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