Tecovirimat - CAS 869572-92-9
Tecovirimat, also known as SIGA-246 and ST-246, is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection. Tecovirimat is a novel antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat has shown efficacy in all small animal and nonhuman primate prophylaxis and therapeutic efficacy models of poxvirus-induced disease tested to date.
Catalog Number: I037080
CAS Number: 869572-92-9
Molecular Formula: C19H15F3N2O3
Molecular Weight:376.3352
Purity: 98.0%
Appearance:Solid powder
* For research use only. Not for human or veterinary use.
Synonym
Synonyms | SIGA-246; SIGA246; SIGA 246; ST-246; ST 246; ST246; Tecovirimat; TPOXX. |
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Property
Molecular Formula: | C19H15F3N2O3 |
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Molecular Weight | 376.3352 |
Solubility | Soluble in DMSO |
Purity | 98.0% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Computed Descriptor
IUPAC Name | 4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop(f)isoindol-2(1H)-yl)-benzamide |
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InChI | InChI=1S/C19H15F3N2O3/c20-19(21,22)9-3-1-8(2-4-9)16(25)23-24-17(26)14-10-5-6-11(13-7-12(10)13)15(14)18(24)27/h1-6,10-15H,7H2,(H,23,25) |
InChIKey | CSKDFZIMJXRJGH-UHFFFAOYSA-N |
SMILES | O=C(NN(C(C1C2C(C3)C3C(C=C2)C41)=O)C4=O)C5=CC=C(C(F)(F)F)C=C5 |