Tecovirimat - CAS 869572-92-9

Tecovirimat, also known as SIGA-246 and ST-246, is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection. Tecovirimat is a novel antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat has shown efficacy in all small animal and nonhuman primate prophylaxis and therapeutic efficacy models of poxvirus-induced disease tested to date.

Catalog Number: I037080

CAS Number: 869572-92-9

Molecular Formula: C19H15F3N2O3

Molecular Weight:376.3352

Purity: 98.0%

Appearance:Solid powder

* For research use only. Not for human or veterinary use.

Synonym

SynonymsSIGA-246; SIGA246; SIGA 246; ST-246; ST 246; ST246; Tecovirimat; TPOXX.

Property

Molecular Formula: C19H15F3N2O3
Molecular Weight376.3352
SolubilitySoluble in DMSO
Purity98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Computed Descriptor

IUPAC Name4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop(f)isoindol-2(1H)-yl)-benzamide
InChIInChI=1S/C19H15F3N2O3/c20-19(21,22)9-3-1-8(2-4-9)16(25)23-24-17(26)14-10-5-6-11(13-7-12(10)13)15(14)18(24)27/h1-6,10-15H,7H2,(H,23,25)
InChIKeyCSKDFZIMJXRJGH-UHFFFAOYSA-N
SMILESO=C(NN(C(C1C2C(C3)C3C(C=C2)C41)=O)C4=O)C5=CC=C(C(F)(F)F)C=C5