Levofloxacin

  • CAT Number: I000113
  • CAS Number: 100986-85-4
  • Molecular Formula: C18H20FN3O4
  • Molecular Weight: 361.4
  • Purity: ≥95%
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Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Catalog Number I000113
CAS Number 100986-85-4
Molecular Formula

C18H20FN3O4

Purity 95%
Target Antibiotic
Solubility DMSO 25 mg/mL; Water 11.2 mg/mL
Storage Store at -20C
InChIKey GSDSWSVVBLHKDQ-JTQLQIEISA-N
Reference

</br>1:Pharmacokinetics of Levofloxacin in Multidrug- and Extensively Drug-Resistant Tuberculosis patients. Van/’t Boveneind-Vrubleuskaya N, Seuruk T, van Hateren K, van der Laan T, Kosterink JGW, van der Werf TS, van Soolingen D, van den Hof S, Skrahina A, Alffenaar JC.Antimicrob Agents Chemother. 2017 May 15. pii: AAC.00343-17. doi: 10.1128/AAC.00343-17. [Epub ahead of print] PMID: 28507117 </br>2:Electrocatalytic properties of N-doped graphite felt in electro-Fenton process and degradation mechanism of levofloxacin. Liu X, Yang D, Zhou Y, Zhang J, Luo L, Meng S, Chen S, Tan M, Li Z, Tang L.Chemosphere. 2017 May 6;182:306-315. doi: 10.1016/j.chemosphere.2017.05.035. [Epub ahead of print] PMID: 28501570 </br>3:Application of Deep Eutectic Solvents in Hybrid Molecularly Imprinted Polymers and Mesoporous Siliceous Material for Solid-Phase Extraction of Levofloxacin from Green Bean Extract. Li X, Row KH.Anal Sci. 2017;33(5):611-617. doi: 10.2116/analsci.33.611. PMID: 28496066 Free Article</br>4:<i>In Vitro</i> Resistance Selection in <i>Shigella flexneri</i> by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin. Allen GP, Harris KA.Antimicrob Agents Chemother. 2017 May 8. pii: AAC.00086-17. doi: 10.1128/AAC.00086-17. [Epub ahead of print] PMID: 28483960 </br>5:[Levofloxacin-based triple therapy versus bismuth-based quadruple therapy in the treatment of <i>Helicobacter pylori</i> as the rescue therapy: a meta analysis]. Zhang M, Chen CY, Wang XT, Lyu B.Zhonghua Nei Ke Za Zhi. 2017 May 1;56(5):368-374. doi: 10.3760/cma.j.issn.0578-1426.2017.05.013. Chinese. PMID: 28460509 </br>6:Easy-Assessment of Levofloxacin and Minocycline in Relevant Biomimetic Media by HPLC-UV Analysis. Matos AC, Pinto RV, Bettencourt AF.J Chromatogr Sci. 2017 Apr 24:1-9. doi: 10.1093/chromsci/bmx033. [Epub ahead of print] PMID: 28444354 </br>7:Cost-effectiveness analysis of oral versus intravenous drip infusion of levofloxacin in the treatment of acute lower respiratory tract infection in Chinese elderly patients. Zhang L, Hu P.Clin Interv Aging. 2017 Apr 12;12:673-678. doi: 10.2147/CIA.S127009. eCollection 2017. PMID: 28442897 Free PMC Article</br>8:Experimental study on the influence of low-frequency and low-intensity ultrasound on the permeability of the Mycobacterium smegmatis cytoderm and potentiation with levofloxacin. Dong Y, Su H, Jiang H, Zheng H, Du Y, Wu J, Li D.Ultrason Sonochem. 2017 Jul;37:1-8. doi: 10.1016/j.ultsonch.2016.12.024. Epub 2016 Dec 19. PMID: 28427611 </br>9:Dry powders for the inhalation of ciprofloxacin or levofloxacin combined with a mucolytic agent for cystic fibrosis patients. Akdag Cayli Y, Sahin S, Buttini F, Balducci AG, Montanari S, Vural I, Oner L.Drug Dev Ind Pharm. 2017 Apr 27:1-12. doi: 10.1080/03639045.2017.1318902. [Epub ahead of print] PMID: 28420285 </br>10:Levofloxacin-Induced Acute Immune-Mediated Thrombocytopenia of Rapid-Onset. Shih AW, Lam AS, Warkentin TE.J Pharm Pract. 2017 Jan 1:897190017702306. doi: 10.1177/0897190017702306. [Epub ahead of print] PMID: 28403679

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