Tauroursodeoxycholate dihydrate

• CAT Number: I019138
• CAS Number: 117609-50-4
• Molecular Formula: C₂₆H₄₉NO₈S
• Molecular Weight: 535.73
• Purity: ≥95%

Tauroursodeoxycholate dihydrate (CAT: I019138) is a chemical compound derived from bile acids. It is a taurine-conjugated form of ursodeoxycholic acid (UDCA). Tauroursodeoxycholate dihydrate has shown various pharmacological activities, including anti-apoptotic, anti-inflammatory, and cytoprotective effects. It has been studied for its potential therapeutic applications in liver diseases, particularly cholestatic liver disorders such as primary biliary cholangitis (PBC). Tauroursodeoxycholate dihydrate has been shown to improve liver function, reduce hepatocyte apoptosis, and modulate bile acid homeostasis. It may also have neuroprotective properties and has been investigated for potential applications in neurodegenerative diseases. Further research is underway to explore its mechanisms of action and therapeutic potential in various conditions.

Reference

[1]. Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK viaPKCα-mediated MKP-1 induction. Cardiovasc Res. 2011 Nov 1;92(2):307-16.[2]. Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. Eur J Vasc Endovasc Surg. 2017 Mar;53(3):337-345.