Tau-aggregation and neuroinflammation-IN-1

For research use only. Not for therapeutic Use.

  • CAT Number: I043835
  • CAS Number: 2175953-98-5
  • Molecular Formula: C25H20N2O7
  • Molecular Weight: 460.44
  • Purity: ≥95%
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Tau-aggregation and neuroinflammation-IN-1(Cat No.:I043835)is a small molecule inhibitor designed to target the aggregation of tau proteins, which play a central role in neurodegenerative diseases like Alzheimer’s disease. This compound also modulates neuroinflammatory pathways, which are often activated in response to tau accumulation. By preventing tau aggregation and reducing neuroinflammation, Tau-aggregation and neuroinflammation-IN-1 holds promise as a therapeutic agent in slowing the progression of tauopathies. It offers a dual-target approach to address both the pathological tau accumulation and the inflammation that contributes to neuronal damage in neurodegenerative disorders.


CAS Number 2175953-98-5
Synonyms

4-[(4aR)-8-acetyl-5,7-dihydroxy-3,4a,6-trimethyl-4-oxo-[1]benzofuro[3,2-f]indazol-1-yl]benzoic acid

Molecular Formula C25H20N2O7
Purity ≥95%
IUPAC Name 4-[(4aR)-8-acetyl-5,7-dihydroxy-3,4a,6-trimethyl-4-oxo-[1]benzofuro[3,2-f]indazol-1-yl]benzoic acid
InChI InChI=1S/C25H20N2O7/c1-10-20(29)18(12(3)28)22-19(21(10)30)25(4)16(34-22)9-15-17(23(25)31)11(2)26-27(15)14-7-5-13(6-8-14)24(32)33/h5-9,29-30H,1-4H3,(H,32,33)/t25-/m0/s1
InChIKey AKUILIKFHHXNNL-VWLOTQADSA-N
SMILES CC1=C(C(=C2C(=C1O)[C@@]3(C(=CC4=C(C3=O)C(=NN4C5=CC=C(C=C5)C(=O)O)C)O2)C)C(=O)C)O
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