Tamoxifen N-oxide

• CAT Number: R005700
• CAS Number: 75504-34-6
• Molecular Formula: C26H29NO2
• Molecular Weight: 387.51
• Purity: ≥95%
• Synonyms: 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine oxide
• InChI: InChI=1S/C26H29NO2/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)29-20-19-27(2,3)28/h5-18H,4,19-20H2,1-3H3/b26-25-
• InChIKey: YAASNACECBQAFW-QPLCGJKRSA-N
• SMILES: CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCC[N+](C)(C)[O-])C3=CC=CC=C3

Tamoxifen N-oxide(CAT: R005700) is a phase I oxidative metabolite of tamoxifen, a selective estrogen receptor modulator (SERM) widely used in breast cancer treatment and research. Formed via N-oxidation, this metabolite provides insights into tamoxifen’s metabolic pathways, biotransformation, and the role of cytochrome P450 enzymes in drug processing. Tamoxifen N-oxide is valuable for pharmacokinetic and toxicological studies, as well as investigations into the bioactivation and detoxification of SERMs. It also aids in the development of analytical methods for drug monitoring and metabolic profiling.