Tamoxifen citrate

• CAT Number: A001049
• CAS Number: 54965-24-1
• Molecular Formula: C₂₆H₂₉NO . C₆H₈O₇
• Molecular Weight: 563.64
• Purity: ≥95%
• Synonyms: ICI 46474 Citrate
• Target: Vitamin D Related/Nuclear Receptor
• Solubility: Soluble in DMSO > 10 mM
• Storage: 3 years -20C powder
• IUPAC Name: 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid
• InChI: InChI=1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-
• InChIKey: FQZYTYWMLGAPFJ-OQKDUQJOSA-N
• SMILES: CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Tamoxifen citrate（Cat No.:A001049）is a selective estrogen receptor modulator (SERM) with the molecular formula C32H37NO8, widely used in the treatment and prevention of estrogen receptor-positive (ER+) breast cancer. It works by competitively binding to estrogen receptors, blocking estrogen’s proliferative effects on breast tissue. Administered orally, tamoxifen is also used to reduce the risk of breast cancer recurrence and in high-risk populations as a preventive measure. Common side effects include hot flashes, fatigue, and an increased risk of thromboembolic events. It remains a cornerstone in hormone-responsive breast cancer therapy.