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TA-02

TA-02

  • CAT Number: I002313
  • CAS Number: 1784751-19-4
  • Molecular Formula: C₂₀H₁₃F₂N₃
  • Molecular Weight: 333.33
  • Purity: ≥95%
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TA-02 (Cat.No:I002313) is a chemical compound known for its potential as a natural killer (NK) cell agonist. It activates NK cells, enhancing their antitumor activity and immune responses. TA-02 has been studied for its therapeutic potential in cancer immunotherapy and shows promise as a candidate for further research in oncology.

Catalog Number I002313
CAS Number 1784751-19-4
Molecular Formula

C₂₀H₁₃F₂N₃

Purity 95%
Target HSC
Solubility 10 mM in DMSO
Storage Store at +4°C
IC50 20 nM
InChI InChI=1S/C20H13F2N3/c21-15-7-5-13(6-8-15)18-19(14-9-11-23-12-10-14)25-20(24-18)16-3-1-2-4-17(16)22/h1-12H,(H,24,25)
InChIKey QIFJOFNVIVQRNJ-UHFFFAOYSA-N
SMILES C1=CC=C(C(=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)F
Reference

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<br>[1]. Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar;80:56-70.

<br>[2]. Filip LACO, et al. 2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis. WO 2015119579 A1.

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