Sulfo-Cy5 amine

• CAT Number: I036801
• CAS Number: 2183440-44-8
• Molecular Formula: C38H52N4O7S2
• Molecular Weight: 740.97
• Purity: ≥95%
• Synonyms: (2E)-1-[6-(6-aminohexylamino)-6-oxohexyl]-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethyl-5-sulfoindol-1-ium-2-yl)penta-2,4-dienylidene]indole-5-sulfonate
• InChI: InChI=1S/C38H52N4O7S2/c1-37(2)30-26-28(50(44,45)46)19-21-32(30)41(5)34(37)16-10-8-11-17-35-38(3,4)31-27-29(51(47,48)49)20-22-33(31)42(35)25-15-9-12-18-36(43)40-24-14-7-6-13-23-39/h8,10-11,16-17,19-22,26-27H,6-7,9,12-15,18,23-25,39H2,1-5H3,(H2-,40,43,44,45,46,47,48,49)
• InChIKey: YAAUASLQACUDFY-UHFFFAOYSA-N
• SMILES: CC1(C2=C(C=CC(=C2)S(=O)(=O)O)[N+](=C1C=CC=CC=C3C(C4=C(N3CCCCCC(=O)NCCCCCCN)C=CC(=C4)S(=O)(=O)[O-])(C)C)C)C

Sulfo-Cy5 amine(CAT: I036801) is a water-soluble derivative of the near-infrared dye Cyanine 5 (Cy5), featuring a reactive primary amine group and sulfonate functionalities for enhanced solubility in aqueous environments. The amine moiety enables covalent conjugation with carboxyl-containing biomolecules through amide bond formation, making it ideal for labeling proteins, antibodies, peptides, and other biological macromolecules. Sulfo-Cy5 amine emits in the NIR region, providing deep tissue penetration and low background fluorescence, which is advantageous for in vitro and in vivo imaging. This dye is widely used in fluorescence microscopy, flow cytometry, and molecular tracking studies for visualizing dynamic biological processes.