Sulfasalazine

• CAT Number: A000909
• CAS Number: 599-79-1
• Molecular Formula: C18H14N4O5S
• Molecular Weight: 398.4
• Purity: ≥95%
• Storage: -20°C
• InChI: 1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,20H,(H,19,22)(H,24,25)/b21-13-
• InChIKey: OQANPHBRHBJGNZ-BKUYFWCQSA-N
• SMILES: C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)O

Sulfasalazine is used in the treatment of inflammatory bowel disease, including ulcerative colitis and Crohn/’s disease. It is also indicated for use in rheumatoid arthritis and used in other types of inflammatory arthritis (e.g. psoriatic arthritis) where it has a beneficial effect. It is often well tolerated compared to other DMARDs. In clinical trials for the treatment of chronic alcoholics, sulfasalazine has been found to reverse the scarring associated with liver cirrhosis.

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