Sulfapyridine

• CAT Number: A000409
• CAS Number: 144-83-2
• Molecular Formula: C11H11N3O2S
• Molecular Weight: 249.29
• Purity: ≥95%
• Target: Antibiotic
• Solubility: Limited solubility
• Storage: -20°C
• InChI: 1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)
• InChIKey: GECHUMIMRBOMGK-UHFFFAOYSA-N
• SMILES: C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N

Sulfapyridine is a sulfonamide antibacterial. At one time it was commonly referred to as M&B. Sulfapyridine is no longer prescribed for treatment of infections in humans. However, it may be used to treat linear IgA disease. It is a good antibacterial drug, but its water solubility is very pH dependent. Thus there is a risk of crystallization within the bladder or urethra, which could lead to pain or blockage. As with other sulfonamides, there is a significant risk of agranulocytosis, and this, rather than the development of resistance by bacteria, is the main reason for its decline in use.

Reference

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