SU11652

For research use only. Not for therapeutic Use.

  • CAT Number: I036748
  • CAS Number: 326914-10-7
  • Molecular Formula: C22H27ClN4O2
  • Molecular Weight: 414.93
  • Purity: ≥95%
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SU11652(Cat No.:I036748)is a small molecule inhibitor that targets receptor tyrosine kinases (RTKs), particularly those involved in angiogenesis and tumor growth. It inhibits the activity of kinases like VEGFR (vascular endothelial growth factor receptor) and PDGFR (platelet-derived growth factor receptor), which are crucial for endothelial cell proliferation, migration, and new blood vessel formation. SU11652 shows promise in cancer therapy by disrupting tumor blood supply, thereby hindering tumor growth and metastasis. It is being studied as a potential treatment for various cancers, including those that exhibit resistance to conventional therapies.


CAS Number 326914-10-7
Synonyms

5-[(Z)-(5-chloro-2-oxo-1H-indol-3-ylidene)methyl]-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide

Molecular Formula C22H27ClN4O2
Purity ≥95%
IUPAC Name 5-[(Z)-(5-chloro-2-oxo-1H-indol-3-ylidene)methyl]-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
InChI InChI=1S/C22H27ClN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-
InChIKey XPLJEFSRINKZLC-ATVHPVEESA-N
SMILES CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\2/C3=C(C=CC(=C3)Cl)NC2=O)C
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