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STROPHANTIDIN 3-Acetate

STROPHANTIDIN 3-Acetate

  • CAT Number: T000046
  • CAS Number: 60-38-8
  • Molecular Formula: C25H34O7
  • Purity: ≥95%
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<p>It is an ATPase inhibitor and a cardiotonic.</p><br />Cardiac glycoside<!–C<SUB>25</SUB>H<SUB>34</SUB>O<SUB>7</SUB>–>, derivative of <b>Strophantidin</b> from plants of the <I>Strophantus</I> genus, Apocynaceae</br><p>IC<sub>50</sub> for cardiac Na<sup>+</sup>/K<sup>+</sup>-ATPase inhibition: 0.4 &amp;mu;M;<br /> IC<sub>50</sub> for renal Na<sup>+</sup>/K<sup>+</sup>-ATPase inhibition: 1.3 &amp;mu;M;</p></br>

Catalog Number T000046
CAS Number 60-38-8
Molecular Formula

C25H34O7

Purity 95%
Solubility In chloroform<br>Slightly in ethanol<br>Not in water and ether
Storage Store at +4C, in dark place;Solution for use: 0.05 %.
Reference

– Kai Yuan Yu, /Inhibition of H+-transporting ATPase, Ca2+-transporting ATPase and H+/K+-transporting ATPase by Strophantidin./ Biochim. Biophys. Acta (1992). 1159(1):109-112 <br /><br />- Mirsalichova et al., /The thermodynamic essence of the reversible inactivation of Na+/K+ transporting ATPase by various digitalis derivatives is relaxation of enzyme conformational energy./ Bioch. Biophys. Acta (1988). 937:335-346<br /><br /><br /><br />

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