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STL127705

STL127705

  • CAT Number: I019175
  • CAS Number: 1326852-06-5
  • Molecular Formula: C₂₂H₂₀FN₅O₄
  • Molecular Weight: 437.42
  • Purity: ≥95%
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STL127705 (Compound L)(Cat.No:I019175) is a Ku 70/80 heterodimer protein inhibitor, inhibits Ku70/80-DNA interaction, with an IC50 of 3.5 μM. STL127705 also inhibits Ku-dependent activation of DNA-PKCS kinase (IC50, 2.5 μM)[1].

Catalog Number I019175
CAS Number 1326852-06-5
Molecular Formula

C₂₂H₂₀FN₅O₄

Purity 95%
Reference

[1]. Weterings E, et al. A novel small molecule inhibitor of the DNA repair protein Ku70/80. DNA Repair (Amst). 2016 Jul;43:98-106.

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