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Steviol

Steviol

  • CAT Number: R060472
  • CAS Number: 471-80-7
  • Molecular Formula: C20H30O3
  • Molecular Weight: 318.5
  • Purity: ≥95%
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Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from <em>S. rebaudiana</em>. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4 (IC<sub>50</sub>s = 11.4, 36.5, 1,000, and 285 μM, respectively). Uptake assays in mouse renal cortical slices yield similar results with IC<sub>50</sub> values of 12.8 and 67.6 μM for hOAT1 and hOAT3, respectively. Due to the use of steviol glycosides as sweeteners, the safety of steviol is widely studied, including its genotoxicity and toxicokinetics.

Catalog Number R060472
CAS Number 471-80-7
Synonyms

(4α)-13-Hydroxy-kaur-16-en-18-oic Acid; 13-Hydroxy-kaur-16-en-18-oic Acid; (-)-Steviol; 13-Hydroxykaurenoic Acid; Ent-13-hydroxy-kauran-16-en-19-oic Acid; NSC 226902

Molecular Formula

C20H30O3

Purity 95%
Storage -20°C
InChIKey QFVOYBUQQBFCRH-IBYIWXLNSA-N

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