Stepharine

• CAT Number: I044796
• CAS Number: 2810-21-1
• Molecular Formula: C18H19NO3
• Molecular Weight: 297.35
• Purity: ≥95%
• Synonyms: (4R)-10,11-dimethoxyspiro[5-azatricyclo[6.3.1.04,12]dodeca-1(12),8,10-triene-2,4′-cyclohexa-2,5-diene]-1′-one
• IUPAC Name: (4R)-10,11-dimethoxyspiro[5-azatricyclo[6.3.1.04,12]dodeca-1(12),8,10-triene-2,4'-cyclohexa-2,5-diene]-1'-one
• InChI: InChI=1S/C18H19NO3/c1-21-14-9-11-5-8-19-13-10-18(6-3-12(20)4-7-18)16(15(11)13)17(14)22-2/h3-4,6-7,9,13,19H,5,8,10H2,1-2H3/t13-/m1/s1
• InChIKey: OGJKMZVUJJYWKO-CYBMUJFWSA-N
• SMILES: COC1=C(C2=C3[C@@H](CC24C=CC(=O)C=C4)NCCC3=C1)OC

Stepharine（Cat No.:I044796）is a natural aporphine alkaloid extracted from plants of the Stephania genus, traditionally used in Asian herbal medicine. It features a tetracyclic structure typical of aporphines and exhibits a variety of pharmacological activities. Stepharine has demonstrated antispasmodic, hypotensive, and neuroprotective effects, and is being studied for its potential in treating neurological disorders such as Parkinson’s disease. It may also influence dopamine receptors and modulate neurotransmission. With its diverse bioactivity and natural origin, stepharine is of significant interest in both pharmacological research and the development of plant-based therapeutic agents.